If you are getting Volax XC, look for a place that explains how to position it while avoiding blood vessels around the chin and a plan that does not inject too much volume at once. In chin trials, effects were maintained 12 months later, but swelling and delayed inflammation can occur depending on volume and injection depth.[1][2][3].
Who is Volax XC suitable for?
Volax XC is a firm hyaluronic acid that projects the chin forward or defines the jawline.[2]In a trial targeting people with recessed chins, 119 people received treatment, and the profile angle 3 months after treatment improved by 2.51 degrees more than the untreated group.[1].
Examples of suitable candidates include a small chin, wanting a masculine jawline, age-related jawline laxity, and similar concerns.[4]However, if the main cause is sagging below the chin, another method may be more appropriate. Whether the clinic identifies the underlying cause first is the key dividing point.
How long do results last, and what evidence supports this?
In the chin, effects remained at 12 months, and duration of 18 months has been reported.[1][4]In specialist experience, it often lasts around 2 years, although duration varies among individuals.[2].
In jawline trials, over 78% of treated patients were satisfied with the overall treatment at 6 months.[5]Chin line volume increased by 6.0 mL in treated patients and decreased by 2.6 mL in untreated patients.[5].
It is important to note that Asian participants in Western trials represented only 0–12.5%.[6]Clinical experience in China is accumulating evidence of efficacy, but comparative research on Japanese facial anatomy remains limited.[6].
Can I inject a large volume all at once?
The approach of dividing into multiple sessions if necessary, rather than injecting large amounts at once, is recommended.[2]Overfilling can stretch tissue and compress thin blood vessels, increasing risk of pain and other complications.[2].
A case was reported where a patient who received 4 mL injected at the same depth in the chin experienced swelling and pain in the chin after dental treatment at 70 days post-injection.[3]This report proposed prevention strategies including limiting volume, dividing into multiple sessions, and varying injection depth.[3].
What should I check regarding injection technique and blood vessel safety?
On the jawline, avoiding facial arteries, and on the chin, avoiding arteries of the lower lip and chin, are key to safety.[2]Therefore, thorough knowledge of facial blood vessel anatomy is essential.[2].
Both thin needles and blunt-tip cannulas are used.[2]Needles allow easier targeting of precise depth, while cannulas may reduce risk of blood vessel injury — the choice depends on the clinical situation.[2].
Hyaluronic acid injection can rarely cause blood vessel occlusion, leading to skin necrosis or blindness.[7]Although the risk of blindness is lower for the chin and jawline compared to other areas, it is not zero.[2]When occlusion occurs, using hyaluronidase (a drug that dissolves hyaluronic acid) in larger amounts, quickly, has been reported as an effective response.[8].
Where should I get it? A checklist when unsure
During consultation, ask about the following points:
Diagnosis: Is the small chin the cause, or will other methods be compared?[4]
Volume plan: Will the clinic explain the volume to inject at once and the plan if spreading over multiple sessions?[2][3]
Injection technique: Will the clinic explain which blood vessels to avoid and whether a needle or cannula will be used?[2]
Contingency: Can hyaluronidase be used immediately if needed?[8]
Follow-up: Can I return for care if swelling occurs after dental work or other procedures?[3]
Pain at the chin or chin angle may occur for 1–2 days after treatment, according to reported guidelines.[2]Knowing this in advance helps avoid unnecessary anxiety.
Whether Volax XC is right for your chin and how much volume is needed cannot be determined from this article alone. During consultation, tell your doctor which features bother you about your profile and whether you have dental treatment scheduled soon, and discuss volume and injection technique together.
- 1Ogilvie P, Sattler G, Gaymans F, Belhaouari L, Weichman BM, Snow S. Safe, Effective Chin and Jaw Restoration With VYC-25L Hyaluronic Acid Injectable Gel. Dermatologic Surgery. 2019. doi:10.1097/DSS.0000000000001960
- 2Bertossi D, Denkova R, Hoo AJS, Loh D, Murdoch M, Shturman Sirota I. Structural Aesthetic Treatment With the Hyaluronic Acid Filler VYC-25L: Global Expert Considerations for Safe and Effective Long-Term Outcomes. Journal of Cosmetic Dermatology. 2025. doi:10.1111/jocd.16555
- 3Xiang H, Wei M, Yi P, Ao R, Sun Y. Delayed Inflammation Occurred Only to VYC-25L After Coinjection of VYC-20L and VYC-25L in an Asian Patient. Plastic and Reconstructive Surgery Global Open. 2025. doi:10.1097/GOX.0000000000007211
- 4Segurado MA, Urdiales-Gálvez F, Benítez PA, Carrasco S, Díaz I, Escoda N, et al. An expert consensus report on the clinical use of the Vycross hyaluronic acid VYC-25L filler. Journal of Cosmetic Dermatology. 2021. doi:10.1111/jocd.14398
- 5Burgess C, Dayan S, Bank D, Weinkle S, Sartor M, Chawla S, Keaney T. Hyaluronic Acid Filler VYC-25L for Jawline Restoration Yields High Satisfaction, Improved Jawline Measurements, and Sustained Effectiveness Across Skin Types, Age, and Gender for up to 12 Months. Aesthetic Surgery Journal. 2025. doi:10.1093/asj/sjae172
- 6Liang Y, Zhan W, Xie Y, Wang D, Li Q, Zhao G. Hyaluronic Acid Injectable Gel VYC-25L Is Safe and Effective for Adults Seeking Chin Enhancement to Correct Chin Retrusion: Results From a Real-world Evidence Study in China. Aesthetic Plastic Surgery. 2025. doi:10.1007/s00266-024-04572-3
- 7Japanese Society of Aesthetic Surgeons, Cosmetic Medical Treatment Guidelines, CQ2-2-1 (Hyaluronic acid filler injection is effective for facial wrinkle treatment, but caution is required due to reports of serious complications such as skin necrosis and blindness resulting from intravascular injection. Recommendation level 2, weakly recommended)
- 8Turcza JF, Bartosińska J, Raczkiewicz D. Critical Ischemia Following Hyaluronic Acid Filler Injection: A Case Report. Journal of Clinical Medicine. 2025. doi:10.3390/jcm14030802